Minimum alveolar concentration (MAC) of xenon in intubated swine
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چکیده
منابع مشابه
Minimum alveolar concentration (MAC) of xenon in intubated swine.
BACKGROUND The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS The study was performed using ten swine (weight 27.8-35.4 kg) anaesthetized with halothane and Xe 0, 15, 30, 40, 50 and 65% in oxyg...
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It has been suggested previously that tramadol increases central nervous system activity and 'lightens' anaesthesia with volatile agents. We assessed the effects of tramadol on the minimum alveolar concentration (MAC) of isoflurane in 56 Wistar rats, instrumented chronically with an arterial and central venous catheter. The MAC of isoflurane was determined using the tail clamp method under thre...
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Minimum alveolar concentration (MAC), served as the vital concept for standard measure of potency for inhaled volatile anesthetic agents, has been employed in anesthetic practice for more than 50 years. A re-consideration in the connotation and influence factors on MAC is introduced in this article. MAC actually indicates “median effective dose (ED50) for immobility”, but it is at least not com...
متن کاملRate of rise of alveolar xenon concentration in man.
The rate of rise of alveolar xenon concentration toward a fixed inspired level was measured in four adult male volunteers. At 1 minute the ratio of end-tidal to inspired xenon concentration was 0.76, at 2 minutes it was 0.38, at 5 minutes it was 0.96, and at 20 minutes it was 0.97. These results agree with those predicted from xenon solubility in blood and tissues, and were closely simulated wi...
متن کاملThermoregulatory thresholds for vasoconstriction in patients anesthetized with various 1-minimum alveolar concentration combinations of xenon, nitrous oxide, and isoflurane.
BACKGROUND Nitrous oxide limits intraoperative hypothermia because the vasoconstriction threshold with nitrous oxide is higher than with equi-minimum alveolar concentrations of sevoflurane or isoflurane, presumably because of its stimulating actions on the sympathetic nervous system. Xenon, in contrast, does not cause sympathetic activation. Therefore, the authors tested the hypothesis that the...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2004
ISSN: 0007-0912
DOI: 10.1093/bja/aeh077